Ultrasound-guided sclerotherapy is an outpatient procedure used to treat varicose veins and other problems caused by venous insufficiency. Ultrasound is used to access a varicose vein under the skin with a very small needle. A medication is mixed with carbon dioxide gas to form foam, which is injected directly into the abnormal vein to close it permanently.

Ultrasound-guided sclerotherapy takes only 15 minutes to perform. Compression stockings are worn for one week after the procedure and patients can resume their normal activities immediately after the procedure. Patients should walk at least 30 minutes per day following ultrasound-guided sclerotherapy.

Ultrasound-guided sclerotherapy is most often used to treat residual, non-bulging varicose veins following radiofrequency ablation. Patients may experience mild pain and burning in the days following sclerotherapy, which is usually managed with anti-inflammatory medications and compression stockings.